Department of Immunology University of Tuebingen Department of Biomathematics

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Prediction Algorithm for Proteasomal Cleavages

PAProC's location within the MHC class I antigen processing pathway. New PAProC
PAProC I - prediction of cleavages by human and yeast 20S proteasomes PAProC II - refined version of PAProC for human 20S proteasomes (constitutive vs. immunoproteasomes)

User information on PAProC functions
Background information on proteasomes and PAProC

PAProC is a prediction tool for cleavages by human and yeast 20S proteasomes, based on experimental cleavage data.

How to cite PAProC:
C. Kuttler, A.K. Nussbaum, T.P. Dick, H.-G. Rammensee, H. Schild, K.P. Hadeler, An algorithm for the prediction of proteasomal cleavages, J. Mol. Biol. 298 (2000), 417-429 , and
A.K. Nussbaum, C. Kuttler, K.P. Hadeler, H.-G. Rammensee, H. Schild, PAProC: A Prediction Algorithm for Proteasomal Cleavages available on the WWW, Immunogenetics 53 (2001), 87-94

For comprehensive background information, please refer to From the test tube to the World Wide Web - The cleavage specificity of the proteasome (A.K. Nussbaum, dissertation, University of Tuebingen, Germany, 2001).

Last update: 22.04.2005 - Version 1.2
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